This haloalkaliphilic archaeon is in the same family as microorganisms like Halobacterium. Study of Natronococcus continues to explore what enzymes are present in order to survive in these conditions, especially since there has not been much literature about enzymes of haloalkaliphiles.
The G + C content for the major chromosome is 64.0% while the minor component has a 55.7% content. The approximate size of the plasmid is 144 kbp.
Natronococcus is a heterotrophic, aerobic organism that can use sugars as a nitrogen source to stimulate growth. Specifically it can fix nitrogen from casamino acids, glucose, ribose, and sucrose and reduces nitrates to nitrites. (not possible to fix nitrogen from carbohydrates)
N. occultus has been isolated from the soda lake Lake Magadi. This halophilic archaeon is partial to environments with 8–30% NaCl with optimum growth at 22%. It also grows in a pH range of 8.5–11 (optimum at 9.5) and a temperature range of 20–50 °C (optimum at 40 °C).