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P12-Tethers-the-Murine-Leukemia-Virus-Pre-integration-Complex-to-Mitotic-Chromosomes-ppat.1003103.s006

509.24063562.580x360

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Summary[edit] DescriptionAPI English: Transition from docking to chromosomes to intra-nuclear movement of MLV PICs in cells exiting mitosis. Mitotic, 2ME2-arrested, wt GFP-infected U/R/RFP-H2A cells were visualized by time-lapse microscopy before (A) and after (B) the addition of Reversine. The same procedure was applied for infected, unsynchronized U/R/RFP-H2A cells before (C) and after (D) natural exit from mitosis; and for unsynchronized U/R/RFP-laminA cells, before and after exit from mitosis (E and F, respectively). The U/R/RFP-H2A cells that exit mitosis and that were infected with D184A GFP (G) are the same cells shown during mitosis in part F of Movie S2. Frequency: 1.8, 1.8, 0.9, 0.9, 1.1, 1.1 and 1.1 fps for A to G, respectively. Date December 2012 Source Movie S4 from Elis E, Ehrlich M, Prizan-Ravid A, Laham-Karam N, Bacharach E (2012). "p12 Tethers the Murine Leukemia Virus Pre-integration Complex to Mitotic Chromosomes". PLOS Pathogens. DOI:10.1371/journal.ppat.1003103. PMID 23300449. PMC: 3531515. Author Elis E, Ehrlich M, Prizan-Ravid A, Laham-Karam N, Bacharach E Permission
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