Burkholderia cenocepacia is a species of Gram-negative bacteria that is common in the environment and may cause disease in plants. It is an opportunistic pathogen and human infections are common in patients with cystic fibrosis and chronic granulomatous disease, and are often fatal. In cystic fibrosis, it can cause "cepacia syndrome" which is characterized by a rapidly progressive fever, uncontrolled bronchopneumonia, weight loss, and possibly death. Originally defined as B. cepacia, the group has now been split into nine species, and B. cenocepacia is one of the most intensively-studied.
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