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Mycobacterium microti

Mycobacterium microti

Description[edit]

Gram-positive, nonmotile and acid-fast rods.

Colony characteristics

  • Variable colony morphology, buff in colour, either rough or smooth.

Physiology

Differential characteristics

  • A commercial hybridisation assay (AccuProbe) to identify members of the M. tuberculosis complex exists.
  • All members of the M. tuberculosis complex share identical 16S rDNA and internal transcribed spacers (ITS) sequences
  • But molecular differentiation is possible by gyrB sequence polymorphism

Pathogenesis[edit]

  • Cause of naturally acquired generalized tuberculosis in voles.
  • Recently van Soolingen et al. reported about the first infections among humans caused by M. microti
  • Losing pathogenicity on repeated subculture.
  • Biosafety level 3

Type strain[edit]

Strain ATCC 19422 = CIP 104256 = NCTC 8710.

References[edit]

  • Reed, G. (1957). "Genus Mycobacterium (species affecting warm-blooded animals except those causing leprosy)". In Breed, R.S.; Murray, E.G.D.; Smith, N.R. Bergey's Manual of Determinative Bacteriology (7th ed.). Baltimore: Williams & Wilkins. pp. 703–4. 
  • van Soolingen D, van der Zanden AG, de Haas PE, et al. (July 1998). "Diagnosis of Mycobacterium microti infections among humans by using novel genetic markers". J. Clin. Microbiol. 36 (7): 1840–5. PMC 104938. PMID 9650922. 
  • "Mycobacterium microti". NCBI Taxonomy Browser. 1806. 


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