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Cheiracanthium are usually pale in colour, and have an abdomen that can range from yellow to beige. Both sexes range in size from 5 to 10 mm. Some yellow sac spiders are attracted to the smell of volatiles in gasoline.
Cheiracanthium is primarily an Old World genus, with many species found from northern Europe to Japan, from Southern Africa to India and Australia. The only known species in the New World are C. inclusum and C. mildei. While the former also occurs in Africa and Réunion, the latter is found in the Holarctic region and Argentina. They can also be found in the lower mainland of British Columbia, Canada 
Cheiracanthium venom is purportedly necrotic, and it could cause a small lesion in humans. However, the necrotic nature and severity of the spider's bite has been disputed. Because of the possibly necrotic nature of the wound, MRSA infection is a danger and victims are advised to seek medical treatment. Painful bites may be incurred from such species as C. punctorium in Europe, C. mildei in Europe and North America, C. inclusum in the Americas, C. lawrencei in South Africa and C. japonicum in Japan.
Attraction to vehicle engines
An unspecified Cheiracanthium species is attracted to the smell of petroleum and has caused problems by weaving webs inside the canister vent of particular models of Mazda vehicles, resulting in blockages and build-up of pressure that could potentially cause fuel leakage from the fuel tank and an increased risk of fire. Mazda issued a voluntary recall of Mazda 6 models built between 2010-2012, to fit them with software which would alert drivers if problems were developing.
- "Gas-loving spider prompts Mazda recall in U.S.". Reuters. March 4, 2011.
- Platnick 2007
- Vetter RS, Isbister GK, Bush SP, Boutin LJ. (2006) Verified bites by yellow sac spiders (genus Cheiracanthium) in the United States and Australia: where is the necrosis? Am. J. Trop. Med. Hyg., 74(6), pp. 1043-1048
- Natural History Museum: Exotic sac spider, Cheiracanthium
- "Spider invasion prompts Mazda software fix". BBC. 7 April 2014. Retrieved 9 April 2014.
- Howell, W. Mike & Jenkins, Ronald L. (2004): Spiders of the US: A photographic guide. ISBN 0-536-75853-0
- Platnick, Norman I. (2007): The world spider catalog, version 8.0. American Museum of Natural History.
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