Depth range (m): 1 - 1
Note: this information has not been validated. Check this *note*. Your feedback is most welcome.
Foodplant / gall
Aceria kuko causes gall of live leaf of Lycium
Foodplant / parasite
amphigenous conidial anamorph of Arthrocladiella mougeotii parasitises live leaf of Lycium
Foodplant / saprobe
immersed, becoming erumpent pycnidium of Microsphaeropsis coelomycetous anamorph of Microsphaeropsis olivacea is saprobic on branch of Lycium
Molecular Biology and Genetics
Statistics of barcoding coverage
Specimens with Sequences:177
Specimens with Barcodes:112
Species With Barcodes:48
Lycium is a genus of flowering plants in the nightshade family, Solanaceae. The genus has a disjunct distribution around the globe, with species occurring on most continents in temperate and subtropical regions. South America has the most species, followed by North America and southern Africa. There are several scattered across Europe and Asia, and one is native to Australia.
The generic name is derived from the Greek word λυκιον (lycion), which was applied by Pliny the Elder (23-79) and Pedanius Dioscorides (ca. 40-90) to a plant known as dyer's buckthorn. It was probably a Rhamnus species and was named for Lycia, the province in which it grew. General common names for the genus include box-thorn, desert-thorn, and wolfberry.
Lycium are shrubs, often thorny, growing 1 to 4 meters tall. The leaves are small, narrow, and fleshy, and are alternately arranged, sometimes in fascicles. Flowers are solitary or borne in clusters. The funnel-shaped or bell-shaped corolla is white, green, or purple in color. The fruit is a two-chambered, usually fleshy and juicy berry which can be red, orange, yellow, or black. It may have few seeds or many. Most Lycium have fleshy, red berries with over 10 seeds, but a few American taxa have hard fruits with two seeds.
While most Lycium are monoecious, producing bisexual flowers with functional male and female parts, some species are gynodioecious, with some individuals bearing bisexual flowers and some producing functionally female flowers.
Lycium has been known to European herbalists since ancient times and species were traded from the Far East to Europe by the Romans already, for example via Ariaca and the port of Barbarikon near today's Karachi, as mentioned in the Periplus of the Erythraean Sea. In his Naturalis historia, Pliny the Elder describes boxthorn as a medicinal plant recommended as a treatment for sore eyes and inflammation, as does Pedanius Dioscorides in his P. Dioscoridae pharmacorum simplicium reique medicae.
Boxthorn (Hebrew אטד 'aTaD) is mentioned in the biblical Book of Proverbs as besetting the paths of the wicked (Proverbs 22:5). In his 1753 publication Species Plantarum, Linnaeus describes three Lycium species: L. afrum, L. barbarum, and L. europaeum.
Lycium, particularly L. barbarum, have long been used in traditional Chinese medicine to treat conditions such as male infertility. The fruit of L. barbatum and L. chinense, known as Goji, has become popular in western cultures for its supposed promotion of weight loss and general longevity. The Chinese tonic Fructus Lycii (Gou-Qi-Zi) is made of the fruit of any of several Lycium species, and is used as a supplement, especially for eye health.
Invasive species include L. ferocissimum, which was introduced to Australia and New Zealand and has become a dense, thorny pest plant there. It injures livestock, harbors pest mammals and insects, and displaces native species.
- In the Muslim text Sahih Muslim, Book 041, Number 6985, the boxthorn, or gharqad (in Arabic), is described as 'the tree of the Jews'. Here is the translation of the text: "The last hour would not come unless the Muslims will fight against the Jews and the Muslims would kill them until the Jews would hide themselves behind a stone or a tree and a stone or a tree would say: Muslim, or the servant of Allah, there is a Jew behind me; come and kill him; but the tree Gharqad would not say, for it is the tree of the Jews."
Formerly placed here
|Wikimedia Commons has media related to Lycium.|
|Wikispecies has information related to: Lycium|
- "Genus Lycium". Taxonomy. UniProt. Retrieved 2009-04-16.
- "Genus: Lycium L.". Germplasm Resources Information Network. United States Department of Agriculture. 2009-09-01. Retrieved 2010-12-13.
- Fukuda, T., et al. (2001). Phylogeny and biogeography of the genus Lycium (Solanaceae): Inferences from chloroplast DNA sequences. Molecular Phylogenetics and Evolution 19(2), 246-58.
- Austin, D. F. (2004). Florida Ethnobotany. CRC Press. p. 677. ISBN 9780849323324.
- Lycium. The Jepson eFlora 2013.
- Lycium. Integrated Taxonomic Information System (ITIS).
- Lycium. Flora of China.
- Levin, R. A. and J. S. Miller. (2005). Relationships within tribe Lycieae (Solanaceae): paraphyly of Lycium and multiple origins of gender dimorphism. American Journal of Botany 92(12), 2044-53.
- Miller, J. S. and D. L. Venable. (2002). The transition to gender dimorphism on an evolutionary background of self-incompatibility: an example from Lycium (Solanaceae). American Journal of Botany 89(12), 1907-15.
- Hitchcock, C. L. (1932). A monographic study of the genus Lycium of the Western Hemisphere. Annals of the Missouri Botanical Garden 19(2/3), 179-348 and 350-66. doi:10.2307/2394155 (First page image).
- Luo, Q., et al. (2006). Lycium barbarum polysaccharides: Protective effects against heat-induced damage of rat testes and H2O2-induced DNA damage in mouse testicular cells and beneficial effect on sexual behavior and reproductive function of hemicastrated rats. Life Sciences 79(7), 613-21.
- Ballarín, S. M., et al. (2011). Anaphylaxis associated with the ingestion of Goji berries (Lycium barbarum). J Investig Allergol Clin Immunol 21(7), 567-70.
- Peng, Y., et al. (2005). Quantification of zeaxanthin dipalmitate and total carotenoids in lycium fruits (Fructus Lycii). Plant Foods for Human Nutrition 60(4), 161-64.
- Lycium ferocissimum (African boxthorn). Invasive Species Compendium. CABI.
- "The Book Pertaining to the Turmoil and Portents of the Last Hour (Kitab Al-Fitan wa Ashrat As-Sa`ah)". Center for Muslim-Jewish Engagement. University of Southern California. Retrieved 2010-12-13.
- "GRIN Species Records of Lycium". Germplasm Resources Information Network. United States Department of Agriculture. Retrieved 2010-12-13.
- "Lycium". Integrated Taxonomic Information System. Retrieved 2010-12-13.
|This article may require cleanup to meet Wikipedia's quality standards. (November 2008)|
Wolfberry, commercially called goji berry, is the common name for the fruit of two very closely related species: Lycium barbarum (Chinese: 寧夏枸杞; pinyin: Níngxià gǒuqǐ) and L. chinense (Chinese: 枸杞; pinyin: gǒuqǐ), two species of boxthorn in the family Solanaceae (which also includes the potato, tomato, eggplant, deadly nightshade, chili pepper, and tobacco). It is native to southeastern Europe and Asia.
|This section does not cite any references or sources. (May 2009)|
Wolfberry species are deciduous woody perennial plants, growing 1–3 m high. L. chinense is grown in the south of China and tends to be somewhat shorter, while L. barbarum is grown in the north, primarily in the Ningxia Hui Autonomous Region, and tends to be somewhat taller.
Leaves and flower
Wolfberry leaves form on the shoot either in an alternating arrangement or in bundles of up to three, each having a shape that is either lanceolate (shaped like a spearhead longer than it is wide) or ovate (egg-like). Leaf dimensions are 7-cm wide by 3.5-cm broad with blunted or round tips.
The flowers grow in groups of one to three in the leaf axils. The calyx (eventually ruptured by the growing berry) consists of bell-shaped or tubular sepals forming short, triangular lobes. The corolla are lavender or light purple, 9–14 mm wide with five or six lobes shorter than the tube. The stamens are structured with filaments longer than the anthers. The anthers are longitudinally dehiscent.
In the northern hemisphere, flowering occurs from June through September and berry maturation from August to October, depending on the latitude, altitude, and climate.
These species produce a bright orange-red, ellipsoid berry 1–2-cm deep. The number of seeds in each berry varies widely based on cultivar and fruit size, containing anywhere between 10–60 tiny yellow seeds that are compressed with a curved embryo. The berries ripen from July to October in the northern hemisphere.
Lycium, the genus name, is derived from the ancient southern Anatolian region of Lycia (Λυκία). The fruit is known in pharmacological references as Lycii fructus, which is Latin for "Lycium fruit".
"Wolfberry" is the most commonly used English common name. The origin of this name is unknown, perhaps resulting from confusion over the genus name Lycium, which resembles "lycos", the Greek word for wolf.
In the English-speaking world, the name "goji berry" has been used since the early 21st century. The word "goji" is an approximation of the pronunciation of gǒuqǐ (枸杞), the name for the berry producing plant in several Chinese dialects, including Hokkien and Shanghainese. This name possibly derives from the same roots as the Persian language term gojeh (گوجه) which means "plum/berry".
Since the early 21st century there has been rapidly growing attention for wolfberries for their nutrient value and antioxidant content. They have been termed a superfruit, which has led to a profusion of consumer products.
The majority of commercially produced wolfberries come from the Ningxia Hui Autonomous Region of north-central China and the Xinjiang Uyghur Autonomous Region of western China, where they are grown on plantations. In Zhongning County, Ningxia, wolfberry plantations typically range between 40 and 400 hectares (100–1000 acres or 500–6000 mu) in area. As of 2005, over 10 million mu have been planted with wolfberries in Ningxia.
Cultivated along the fertile aggradational floodplains of the Yellow River for more than 600 years, Ningxia wolfberries have earned a reputation throughout Asia for premium quality sometimes described commercially as "red diamonds". Government releases of annual wolfberry production, premium fruit grades, and export are based on yields from Ningxia, the region recognized with
- The largest annual harvest in China, accounting for 42% (13 million kilograms, 2001) of the nation's total yield of wolfberries, estimated at approximately 33 million kilograms (72 million pounds) in 2001.
- Formation of an industrial association of growers, processors, marketers, and scholars of wolfberry cultivation to promote the berry's commercial and export potential.
- The nation's only source of therapeutic grade ("superior-grade") wolfberries used by practitioners of traditional Chinese medicine.
In addition, commercial volumes of wolfberries grow in the Chinese regions of Inner Mongolia, Qinghai, Gansu, Shaanxi, Shanxi, and Hebei. When ripe, the oblong, red berries are tender and must be picked carefully or shaken from the vine into trays to avoid spoiling. The fruits are preserved by drying them in full sun on open trays or by mechanical dehydration employing a progressively increasing series of heat exposure over 48 hours.
Wolfberries are celebrated each August in Ningxia with an annual festival coinciding with the berry harvest. Originally held in Ningxia's capital, Yinchuan, the festival has been based since 2000 in Zhongning County, an important center of wolfberry cultivation for the region. As Ningxia's borders merge with three deserts, wolfberries are also planted to control erosion and reclaim irrigable soils from desertification.
China, the main supplier of wolfberry products in the world, had total exports generating US$120 million in 2004. This production derived from 82,000 hectares farmed nationwide, yielding 95,000 tons of wolfberries.
Pesticide and fungicide use
Organochlorine pesticides are conventionally used in commercial wolfberry cultivation to mitigate destruction of the delicate berries by insects. Since the early 21st century, high levels of insecticide residues (including fenvalerate, cypermethrin, and acetamiprid) and fungicide residues (such as triadimenol and isoprothiolane), have been detected by the United States Food and Drug Administration in some imported wolfberries and wolfberry products of Chinese origin, leading to the seizure of these products.
China's Green Food Standard, administered by the Chinese Ministry of Agriculture's China Green Food Development Center, does permit some amount of pesticide and herbicide use. Agriculture in the Tibetan plateau (where many "Himalayan" or "Tibetan"-branded berries originate) conventionally uses fertilizers and pesticides, making organic claims for berries originating here dubious.
The Duke of Argyll introduced Lycium barbarum into the United Kingdom in the 1730s where it is known as Duke of Argyll's Tea Tree. It was and still is used for hedging, especially in coastal districts. Its red berries are attractive to a wide variety of British birds.
The plant continues to grow wild in UK hedgerows. On 15 January 2003, the Department for Environment, Food and Rural Affairs launched a project to improve the regulations protecting traditional countryside hedgerows, and specifically mentioned Duke of Argyll's Tea Tree as one of the species to be found growing in hedges located in Suffolk Sandlings, Hadleigh, Bawdsey, near Ipswich, and Walberswick.
On June 18, 2007, the FSA (UK Food Standards Agency) stated that there was a significant history of the fruit being consumed in Europe before 1997, and has removed it from the Novel Foods list. It is now legal to sell the wolfberry in the UK as a food as reported by the British Food Standards Agency, but see section below: Marketing claims under scrutiny in Europe.
Importation of mature plants
Importation of wolfberry plants into the United Kingdom from most countries outside Europe is illegal, due to the possibility they could be vectors of diseases attacking Solanaceae crops, such as potato or tomato.
Wolfberries are usually sold in open boxes and small packages in dried form.
As a food, dried wolfberries are traditionally cooked before consumption. Dried wolfberries are often added to rice congee and almond jelly, as well as used in Chinese tonic soups, in combination with chicken or pork, vegetables, and other herbs such as wild yam, Astragalus membranaceus, Codonopsis pilosula, and licorice root. The berries are also boiled as an herbal tea, often along with chrysanthemum flowers and/or red jujubes, or with tea, particularly pu-erh tea, and packaged teas are also available.
At least one Chinese company also produces wolfberry beer, and New Belgium Brewery makes their seasonal Springboard ale with wolfberries used as flavoring. Since the early 21st century, an instant coffee product containing wolfberry extract has been produced in China.
Preliminary medical research
Marketing literature for wolfberry products including several "goji juices" suggest that wolfberry polysaccharides have biological effects and possible health benefits, although no such claims have been supported by peer-reviewed research or approved by any regulatory agency.
A 2008 pilot study indicated that parametric data did not show significant differences between subjects receiving Lycium barbarum berry juice and subjects receiving a placebo; the authors, nevertheless, concluded that subjective measures had been affected. This study was subject to various criticisms concerning its experimental design and interpretations.
Published studies have also reported biological effects of Lycium barbarum in animal models, and speculated from this basic research that there may be potential benefits against cardiovascular and inflammatory diseases, vision-related diseases (such as age-related macular degeneration and glaucoma) or from neuroprotective, anticancer or immunomodulatory activity.
In Traditional Chinese Medicine, Lycium leaves may be used in a tea, together with the root bark (called dìgǔpí; 地 骨 皮). A glucopyranoside (namely (+)-Lyoniresinol-3α-O-β-d-glucopyranoside) and phenolic amides (dihydro-N-caffeoyltyramine, trans-N-feruloyloctopamine, trans-N-caffeoyltyramine and cis-N-caffeoyltyramine) isolated from wolfberry root bark have inhibitory activity in vitro against human pathogenic bacteria and fungi.
Two published case reports described elderly women who experienced increased bleeding, expressed as an elevated INR, after drinking quantities of wolfberry tea. Further in vitro testing revealed that the tea inhibited warfarin metabolism, providing evidence for possible interaction between warfarin and undefined wolfberry phytochemicals.
Atropine, a toxic alkaloid found in other members of the Solanaceae family, occurs naturally in wolfberry fruit. The atropine concentrations of berries from China and Thailand was tested and found to be variable, with a maximum content of 19 ppb, well below a toxic level. However, misidentified or adulterated samples with higher atropine levels may explain earlier, much higher, measurements.
|This section needs additional citations for verification. (April 2011)|
Micronutrients and phytochemicals
Wolfberries contain many nutrients and phytochemicals including
- 11 essential and 22 trace dietary minerals
- 18 amino acids
- 6 essential vitamins
- 8 polysaccharides and 6 monosaccharides
- 5 unsaturated fatty acids, including the essential fatty acids, linoleic acid and alpha-linolenic acid
- beta-sitosterol and other phytosterols
- 5 carotenoids, including beta-carotene and zeaxanthin (below), lutein, lycopene and cryptoxanthin, a xanthophyll
- numerous phenolic pigments (phenols) associated with antioxidant properties
Select examples given below are for 100 grams of dried berries.
- Calcium. Wolfberries contain 112 mg per 100 gram serving, providing about 8–10% of the Dietary Reference Intake (DRI).
- Potassium. Wolfberries contain 1,132 mg per 100 grams dried fruit, giving about 24% of the DRI.
- Iron. Wolfberries have 9 mg iron per 100 grams (100% DRI).
- Zinc. 2 mg per 100 grams dried fruit (18% DRI).
- Selenium. 100 grams of dried wolfberries contain 50 micrograms (91% DRI)
- Riboflavin (vitamin B2). At 1.3 mg, 100 grams of dried wolfberries provide 100% of DRI.
- Vitamin C. Vitamin C content in dried wolfberries has a wide range (from different sources) from 29 mg per 100 grams to as high as 148 mg per 100 grams (respectively, 32% and 163% DRI).
Wolfberries also contain numerous phytochemicals for which there are no established DRI values. Examples:
- Beta-carotene: 7 mg per 100 grams dried fruit.
- Zeaxanthin. Reported values for zeaxanthin content in dried wolfberries vary considerably, from 2.4 mg per 100 grams to 82.4 mg per 100 grams to 200 mg per 100 grams. The higher values would make wolfberry one of the richest edible plant sources known for zeaxanthin content. Up to 77% of total carotenoids present in wolfberry exist as zeaxanthin.
- Polysaccharides. Polysaccharides are a major constituent of wolfberries, representing up to 31% of pulp weight.
- Endogenous lipid peroxidation, and decreased antioxidant activities, as assessed by superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px) and total antioxidant capacity (TAOC), and immune function were observed in aged mice and restored to normal levels in Lycium polysaccharide-treated groups. Antioxidant activities of Lycium barbarum polysaccharides were found to be comparable with normal antioxidant, vitamin C. Furthemore, adding vitamin C to the polysaccharide treatment further increased in vivo antioxidant activity of the polysaccharides.
Marketers[which?] of some wolfberry products claim that polysaccharides have specific physiological roles mediated by specialized cell receptors "master" control properties over other bioactive chemicals and cells. Characteristic spectral peaks are claimed to define one berry's geographic origin from another.
These assertions are an important marketing message for wolfberry products branded as Tibetan Goji Berries or Himalayan Goji Juice. Such statements, however, have no scientific evidence published under peer-review and are not compliant with regulatory guidelines for marketing natural food products (see below, Marketing claims under scrutiny in Europe, Canada and the United States).
Functional food and beverage applications
It is often cultivated for a variety of food and beverage applications within China, but increasingly today for export as dried berries, juice, and pulp or grounds. Wolfberries are prized for their versatility of color and nut-like taste in common meals, snacks, beverages, and medicinal applications. A major effort is underway in Ningxia, China to process wolfberries for “functional” wine.
Since the early 21st century, the dried fruit has been marketed in the West as a health food (typically under the name "Tibetan goji berry"), often accompanied by scientifically unsupported claims regarding its purported health benefits.
Its most claimed nutritional attribute is an exceptional level of vitamin C, to be among the highest in natural plants. However, it was demonstrated by independent assays on dried berries to be quite variable, in a range of 29–148 mg per 100 grams of fruit. This level is comparable to many citrus fruits and strawberries as well as numerous other fruits and berries.
Companies marketing the berries often also include the unsupported myth that a Chinese man named Li Qing Yuen, who was said to have consumed wolfberries daily, lived to the age of 252 years (1678–1930).
Commercial products marketed outside Asia
Typical of many exotic fruits being introduced into western food and beverage commerce, wolfberry is best known as a juice marketed over the Internet since 2002, often via multi-level marketing that asserts its health benefits. There is an increasing presence of wolfberry in health food stores and grocery markets in many countries.
While juice prepared entirely from fresh wolfberries is rare, blends containing several other berry and fruit juices are used for nearly all "wolfberry" juice products, many of which are nevertheless labeled as "goji juice". The percentage of wolfberry contained in these juices is generally not stated on the labels of such products.
Other wolfberry consumer applications are
- Dried berries (pictured above)
- Berry pieces in granola bars and
- Skin soap (made from seed oils)
- Yogurt products
Commercial suppliers have processed wolfberry as
- An additive for manufacturing
- Juice concentrate
- Whole fruit purée
- Powders from juice or juice concentrate made from spray drying
- Pulp powders
- Whole or ground seeds
- Seed oils (as with grape seed oil), and essential oils derived from seeds).
Marketing claims under scrutiny in Europe
In February 2007, the Food Standards Agency (FSA) of the United Kingdom, an advisor for food safety to the European Food Safety Authority of the European Union (EU), published an inquiry to retailers and health food stores requesting evidence of significant use of wolfberries in Europe before 1997. This period would document a safety history and evaluate how "novel" the berries are in the EU, affecting their authorization status for sale.
Proponents hoped this review would provide important safeguards for consumers by checking whether new foods are suitable for the whole population, including people with food allergies. Opponents on the other hand feared it would limit consumer choice and protect monopolistic interests rather than the public. Food safety in the EU relies importantly on a scientific basis for label information on foods like wolfberries that may be claimed to furnish health benefits.
Marketing claims under scrutiny in Canada and the United States
By one specific example in the CBC interview, Earl Mindell (then working for direct-marketing company FreeLife International, Inc.) claimed the Memorial Sloan-Kettering Cancer Center in New York had completed clinical studies showing that use of wolfberry juice would prevent 75% of human breast cancer cases, a false statement. There are preliminary laboratory studies and one Chinese clinical trial.
During 2006, the U.S. Food and Drug Administration (FDA) placed two goji juice distributors on notice with warning letters about marketing claims. These statements were in violation of the United States Food, Drug and Cosmetic Act [21 USC/321 (g)(1)] because they "establish the product as a drug intended for use in the cure, mitigation, treatment, or prevention of disease" when wolfberries or juice have had no such scientific evaluation. Additionally stated by the FDA, the goji juice was "not generally recognized as safe and effective for the referenced conditions" and therefore must be treated as a "new drug" under Section 21(p) of the Act. New drugs may not be legally marketed in the United States without prior approval of the FDA.
On May 29, 2009, a class action lawsuit was filed against FreeLife in the United States District Court of Arizona. This lawsuit alleges false claims, misrepresentations, false and deceptive advertising and other issues regarding FreeLife’s Himalayan Goji Juice, GoChi, and TaiSlim products. This lawsuit seeks remedies for consumers who have purchased these products over the past several years.
- Gouqi jiu
- List of culinary fruits
- Sea buckthorn – another medicinal plant that somewhat resembles Wolfberry
- Flint, Harrison Leigh (1997). "Lycium barbarum". Landscape plants for eastern North America: exclusive of Florida and the immediate Gulf Coast. Chichester: John Wiley & Sons. p. 326. ISBN 978-0-471-59919-7. http://books.google.com/books?id=Q1_fAywb_bkC&pg=PA326.
- Environment and Plant Life in Indian Desert, David N. Sen, Geobios International, 1982
- GRIN Taxonomy for Lycium barbarum, United States Department of Agriculture Germplasm Resources Information Network
- Huxley, A., ed. (1992). New RHS Dictionary of Gardening. Macmillan ISBN 0-333-47494-5.
- McNally A. Superfoods market set to double by 2011, NutraIngredients.com-Europe, October 8, 2007
- Runestad T. Functional Ingredients market overview, Functional Ingredients, October 2007
-  Xinhua News Agency, Opening ceremonies of Ningxia wolfberry festival, August 3, 2005.
-  Staff reporter, Wolfberry festival to be held in Ningxia, China Daily, July 19, 2004.
-  Staff reporter, China's first provincial-level wolfberry association established, People's Daily Onlne, August 19, 2001.
-  Yunyun L. Dry no more. BeijingReview.com.cn, October 11, 2008.
- IA #99-08, Revision to Import Alert #99-08, "Detention Without Physical Examination of Processed Products for Pesticides"
- Pathbreaking Newsletter Promotes Development of Organic Sector in China Lila Buckley. Worldwatch Institute. 28 February 2006.
- GAIN Report #CH1072. Dueling Standards for Organic Foods 2001 Ralph Bean and Xiang Qing. USDA Global Agriculture Information Network Foreign Agricultural Service. 12 Dec 2001.
- The Movement Toward Organic Herb Cultivation in China Subhuti Dharmananda. Institute for Traditional Medicine. January 2004.
-  Staff Reporter. The commercial legend of goji. Selling a Chinese crop under the Tibetan flag. TibetInfoNet, July 29, 2007.
- A Touch Of Argyll In Norfolk Julia Page in The Corncrake, Colonsay , Scotland " I was intrigued to discover that the common name of lycium halimifolium is the Duke of Argyll's Tea-tree or Teaplant and was keen to discover how this name came about. I succeeded with the help of my friend Craig ( nice Scottish name ) at Kew Gardens Library and a historical Who's Who. Accessed November 2006
- Government Launches Consultation On Future Of Legal Protection For Hedgerows Department for Environment, Food and Rural Affairs, 15 January 2003. Retrieved 6 September 2006.
- The Novel Foods and Novel Food Ingredients Regulations 1997
- Food Standards Agency, June 2007, Responses on goji berries reviewed
- Department for Environment, Food and Rural Affairs, April, 2008. Prohibited Import of Goji Plants. April 30, 2008
- Several bottles of gǒuqǐ jiǔ www.chong-yang.com. Retrieved 25 January 2007.
- Bottle of gǒuqǐ jiǔ data.bip.und.cn. Retrieved 25 January 2007.
- Amagase H, Nance DM (May 2008). "A randomized, double-blind, placebo-controlled, clinical study of the general effects of a standardized Lycium barbarum (Goji) Juice, GoChi". J Altern Complement Med 14 (4): 403–12. doi:10.1089/acm.2008.0004. PMID 18447631.
- Daniells S. (October 2008). "Questions raised over Goji science.". NutraIngredients.com-USA. http://www.nutraingredients-usa.com/Research/Questions-raised-over-Goji-science.
- Wu SJ, Ng LT, Lin CC (December 2004). "Antioxidant activities of some common ingredients of traditional chinese medicine, Angelica sinensis, Lycium barbarum and Poria cocos". Phytother Res 18 (12): 1008–12. doi:10.1002/ptr.1617. PMID 15742346.
- Jia YX, Dong JW, Wu XX, Ma TM, Shi AY (June 1998). "[The effect of lycium barbarum polysaccharide on vascular tension in two-kidney, one clip model of hypertension]" (in Chinese). Sheng Li Xue Bao 50 (3): 309–14. PMID 11324572.
- Luo Q, Li Z, Huang X, Yan J, Zhang S, Cai YZ (July 2006). "Lycium barbarum polysaccharides: Protective effects against heat-induced damage of rat testes and H2O2-induced DNA damage in mouse testicular cells and beneficial effect on sexual behavior and reproductive function of hemicastrated rats". Life Sci. 79 (7): 613–21. doi:10.1016/j.lfs.2006.02.012. PMID 16563441.
- Cheng CY, Chung WY, Szeto YT, Benzie IF (January 2005). "Fasting plasma zeaxanthin response to Fructus barbarum L. (wolfberry; Kei Tze) in a food-based human supplementation trial". Br. J. Nutr. 93 (1): 123–30. doi:10.1079/BJN20041284. PMID 15705234. http://journals.cambridge.org/abstract_S0007114505000188.
- Chan HC, Chang RC, Koon-Ching Ip A, et al. (January 2007). "Neuroprotective effects of Lycium barbarum Lynn on protecting retinal ganglion cells in an ocular hypertension model of glaucoma". Exp. Neurol. 203 (1): 269–73. doi:10.1016/j.expneurol.2006.05.031. PMID 17045262.
- Yu MS, Leung SK, Lai SW, et al. (2005). "Neuroprotective effects of anti-aging oriental medicine Lycium barbarum against beta-amyloid peptide neurotoxicity". Exp. Gerontol. 40 (8–9): 716–27. doi:10.1016/j.exger.2005.06.010. PMID 16139464.
- Gan L, Hua Zhang S, Liang Yang X, Bi Xu H (April 2004). "Immunomodulation and antitumor activity by a polysaccharide-protein complex from Lycium barbarum". Int. Immunopharmacol. 4 (4): 563–9. doi:10.1016/j.intimp.2004.01.023. PMID 15099534.
- He YL, Ying Y, Xu YL, Su JF, Luo H, Wang HF (September 2005). "[Effects of Lycium barbarum polysaccharide on tumor microenvironment T-lymphocyte subsets and dendritic cells in H22-bearing mice"] (in Chinese). Zhong Xi Yi Jie He Xue Bao 3 (5): 374–7. doi:10.3736/jcim20050511. PMID 16159572. http://www.jcimjournal.com/en/showAbstrPage.aspx?articleid=428.
- Lee DG, Park Y, Kim MR, et al. (July 2004). "Anti-fungal effects of phenolic amides isolated from the root bark of Lycium chinense". Biotechnol. Lett. 26 (14): 1125–30. doi:10.1023/B:BILE.0000035483.85790.f7. PMID 15266117.
- Lee DG, Jung HJ, Woo ER (September 2005). "Antimicrobial property of (+)-lyoniresinol-3alpha-O-beta-D-glucopyranoside isolated from the root bark of Lycium chinense Miller against human pathogenic microorganisms". Arch. Pharm. Res. 28 (9): 1031–6. doi:10.1007/BF02977397. PMID 16212233.
- Lam AY, Elmer GW, Mohutsky MA (October 2001). "Possible interaction between warfarin and Lycium barbarum L". Ann Pharmacother 35 (10): 1199–201. doi:10.1345/aph.1Z442. PMID 11675844.
- Leung H, Hung A, Hui AC, Chan TY (May 2008). "Warfarin overdose due to the possible effects of Lycium barbarum L.". Food Chem. Toxicol. 46 (5): 1860–2. doi:10.1016/j.fct.2008.01.008. PMID 18281140.
- Adams, M; Wiedenmann, M; Tittel, G; Bauer, R. (September 2006). "HPLC-MS trace analysis of atropine in Lycium barbarum berries". Phytochem Anal 17 (5): 279–83. doi:10.1002/pca.915. PMID 17019928.
- Lam K-W, But P (1999). "The content of zeaxanthin in Gou Qi Zi, a potential health benefit to improve visual acuity". Food Chem. 67 (2): 173–6. doi:10.1016/S0308-8146(99)00119-3.
- Weller P, Breithaupt DE (November 2003). "Identification and quantification of zeaxanthin esters in plants using liquid chromatography-mass spectrometry". J. Agric. Food Chem. 51 (24): 7044–9. doi:10.1021/jf034803s. PMID 14611169.
- Peng Y, Ma C, Li Y, Leung KS, Jiang ZH, Zhao Z (December 2005). "Quantification of zeaxanthin dipalmitate and total carotenoids in Lycium fruits (Fructus Lycii)". Plant Foods Hum Nutr 60 (4): 161–4. doi:10.1007/s11130-005-9550-5. PMID 16395626.
- [http://lpi.oregonstate.edu/infocenter/phytochemicals/carotenoids/#metabolism "Carotenoids Alpha-Carotene, Beta-Carotene, Beta-Cryptoxanthin, Lycopene, Lutein, and Zeaxanthin"]. http://lpi.oregonstate.edu/infocenter/phytochemicals/carotenoids/#metabolism.
- Li Z, Peng G, Zhang S (July 1998). "[Separation and determination of carotenoids in Fructus lycii by isocratic non-aqueous reversed-phase liquid chromatography]" (in Chinese). Se Pu 16 (4): 341–3. PMID 11367765.
- Li XM, Ma YL, Liu XJ (May 2007). "Effect of the Lycium barbarum polysaccharides on age-related oxidative stress in aged mice". J Ethnopharmacol 111 (3): 504–11. doi:10.1016/j.jep.2006.12.024. PMID 17224253.
- Mindell, 2005
- Linus Pauling Institute, Micronutrient Information Center
- Agency seeks evidence of goji berry consumption, UK Food Standards Agency, February 2007
- 'Miracle' goji berries face ban under EU red tape, The Daily Mail, February 2007
- Nutrition and health claims, European Food Safety Authority, May 2007
- Responses on goji berries reviewed, UK Food Standards Agency, June 2007
- Goji berries, UK Food Standards Agency, June 2007
- CBC News. http://www.cbc.ca/marketplace/2007/01/goji.html.
- Gan L, Wang J, Zhang S (November 2001). "[Inhibition the growth of human leukemia cells by Lycium barbarum polysaccharide]" (in Chinese). Wei Sheng Yan Jiu 30 (6): 333–5. PMID 12561612.
- Tang W, Hemm I, Bertram B (March 2003). "Recent development of antitumor agents from Chinese herbal medicines. Part II. High molecular compounds(3)". Planta Med. 69 (3): 193–201. doi:10.1055/s-2003-38494. PMID 12677520.
- Cao GW, Yang WG, Du P (November 1994). "[Observation of the effects of LAK/IL-2 therapy combining with Lycium barbarum polysaccharides in the treatment of 75 cancer patients (with abstract in English)]" (in Chinese). Zhonghua Zhong Liu Za Zhi 16 (6): 428–31. PMID 7720497.
- US FDA Letter to Dynamic Health Laboratories, Inc.
- US FDA, Letter to Healthsuperstore.com
- "Federal Food, Drug, and Cosmetic Act (FD&C Act)". http://www.fda.gov/RegulatoryInformation/Legislation/FederalFoodDrugandCosmeticActFDCAct/default.htm.
- United States District Court for the District of Arizona (May 29, 2009). "Class action lawsuit against FreeLife International, Inc.". http://www.gojitrees.com/FreeLifeClassActionLawsuit%5B1%5D.pdf. Retrieved 2009-10-31.
- Class-Action Suit Filed against FreeLife and Earl Mindel
- Ai, Changshan (2002). Zhi Bu Liang Yi Hua Gou Qi (A Word About Lycium chinense, Effective for Therapy and Nutrition). Changchun, China: Jilin Ke Xue Ji Shu Chu Ban She. ISBN 7-5384-2402-4. ISBN 978-7-5384-2402-7.
- Gross, P.M./Zhang, R./Zhang, X. (2006). Wolfberry: Nature's Bounty of Nutrition and Health. BookSurge Publishing. ISBN 978-1-4196-2048-5
- Oyama, Sumita (1964). Kuko o Aishite Junen (Lycium chinense in Favorable Use for Ten Years). Tokyo, Japan: Shufu no Tomosha.
- Shufo no Tomosha (1963). Kuko no koyo (Medicinal and Therapeutic Effects of Lycium chinense). Tokyo, Japan.
- Takayama, Eiji (1966). Jinsei no Honbutai wa Rokujissai Kara: Furo Choju Kuko no Aiyo (The Real Stage in Life Begins at Sixty: Habitual Use of Lycium chinense for Longevity). Tokyo, Japan: Koyo Shobo
- Zhang, Yanbo (2000). Molecular Approach to the Authentication of Lycium barbarum and its Related Species. M. Phil. thesis. Hong Kong, China: Hong Kong Baptist University
- Zhao, Yue (2005). The Market Prospect of Ningxia Wolfberry/Wolfberry Products in China. Thesis. Netherlands: University of Professional Education Larenstein Deventer.
To request an improvement, please leave a comment on the page. Thank you!