Molecular Biology and Genetics

Molecular Biology

Statistics of barcoding coverage

Barcode of Life Data Systems (BOLD) Stats
                                        
Specimen Records:674Public Records:304
Specimens with Sequences:631Public Species:32
Specimens with Barcodes:600Public BINs:46
Species:48         
Species With Barcodes:45         
          
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Statistics of barcoding coverage: Lonomia electraDHJ01

Barcode of Life Data Systems (BOLDS) Stats
Public Records: 68
Specimens with Barcodes: 92
Species With Barcodes: 1
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Statistics of barcoding coverage: Lonomia dh3

Barcode of Life Data Systems (BOLDS) Stats
Public Records: 0
Specimens with Barcodes: 1
Species With Barcodes: 1
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Statistics of barcoding coverage: Lonomia Janzen01

Barcode of Life Data Systems (BOLDS) Stats
Public Records: 0
Specimens with Barcodes: 8
Species With Barcodes: 1
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Statistics of barcoding coverage: Lonomia dh2

Barcode of Life Data Systems (BOLDS) Stats
Public Records: 0
Specimens with Barcodes: 1
Species With Barcodes: 1
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Statistics of barcoding coverage: Lonomia dh1

Barcode of Life Data Systems (BOLDS) Stats
Public Records: 0
Specimens with Barcodes: 3
Species With Barcodes: 1
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Statistics of barcoding coverage: Lonomia sp1

Barcode of Life Data Systems (BOLDS) Stats
Public Records: 1
Specimens with Barcodes: 2
Species With Barcodes: 1
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Statistics of barcoding coverage: Lonomia electraDHJ02

Barcode of Life Data Systems (BOLDS) Stats
Public Records: 0
Specimens with Barcodes: 4
Species With Barcodes: 1
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Barcode data: Lonomia electraDHJ01

The following is a representative barcode sequence, the centroid of all available sequences for this species.


There are 83 barcode sequences available from BOLD and GenBank.  Below is a sequence of the barcode region Cytochrome oxidase subunit 1 (COI or COX1) from a member of the species.  See the BOLD taxonomy browser for more complete information about this specimen and other sequences.

NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNACTTCCTTAAGACTTCTAATTCGAGCTGAATTAGGAACCCCAGGCTCTTTAATCGGAGATGATCAAATTTATAATACTATTGTTACAGCTCATGCTTTTATTATAATTTTTTTTATAGTTATACCTATTATAATTGGAGGATTTGGAAATTGATTAGTCCCTCTAATACTAGGAGCTCCTGACATAGCATTCCCTCGAATAAATAATATAAGATTTTGACTTCTCCCCCCCTCTTTAACTTTACTAATTTCGAGTAGTATTGTAGAAAGTGGAGCTGGAACAGGATGAACTGTATACCCTCCTTTATCTTCTAATATTGCTCATGGGGGCTCTTCTGTTGATCTAGCTATTTTTTCTCTTCATTTAGCTGGAATTTCATCAATTTTAGGAGCTATTAATTTTATTACAACTATTATTAATATACGATTAAACAATATTTTTTTTGACCAAATACCTCTATTTGTTTGATCTGTAGGAATTACAGCCTTCCTTTTACTACTCTCTCTCCCTGTTTTAGCCGGAGCTATCACCATACTTTTAACAGATCGTAACCTAAACACCTCTTTTTTTGACCCTGCGGGAGGGGGAGATCCTATTCTTTACCAACATTTATTTNNNN
-- end --

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Barcode data

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Locations of barcode samples

Collection Sites: world map showing specimen collection locations for Lonomia

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Wikipedia

Lonomia

The genus Lonomia is a moderate-sized group of fairly cryptic saturniid moths from South America, famous not for the adults, but for their highly venomous caterpillars, which are responsible for a few deaths each year (e.g., [1]), especially in southern Brazil, and the subject of hundreds of published medical studies. They are commonly known as Giant Silkworm Moth, a name also used for a wide range of other Saturniid moths.[1]

Description[edit]

The caterpillars are themselves extremely cryptic, blending in against the bark of trees, where the larvae commonly aggregate. The larvae, like most hemileucines, are covered with urticating hairs, but these caterpillars possess a uniquely potent anticoagulant venom.

Toxicity[edit]

A typical envenomation incident involves a person unknowingly leaning against, placing their hand on, or rubbing their arm against a group of these caterpillars that are gathered on the trunk of a tree. The effects of a dose from multiple caterpillars can be dramatic and severe, including massive internal hemorrhaging, renal failure, and hemolysis. The resulting medical syndrome is sometimes called Lonomiasis.

To date, no one has calculated the LD50 values of Lonomia venom; the rate of human fatality has been documented as 1.7%.

While there are more than a dozen species in the genus, the most troublesome species is Lonomia obliqua, and it is this species on which most of the medical research has centered. As anticoagulants have some very beneficial applications (e.g., prevention of life-threatening blood clots), a fair bit of the research is motivated by the possibility of deriving some pharmaceutically valuable chemicals from the toxin.

Species[edit]

Notes[edit]

  1. ^ Meyer, W.L. (May 1, 1996), "Chapter 23: Most Toxic Insect Venom", Book of Insect Records, Gainsevuille, Florida: Department of Entomology & Nematology, University of Florida, retrieved March 18, 2011 

References[edit]

  • American Journal of Tropical Medicine & Hygiene article on hemolytic effects
  • Arocha-Pinango C.L., Guerrero B. (2001) Lonomia genus caterpillar envenomation: clinical and biological aspects. Haemostasis 31(3-6):288-93.
  • Gamborgi G.P., Metcalf E.B., Barros E.J. (2006) Acute renal failure provoked by toxin from caterpillars of the species Lonomia obliqua. Toxicon 47(1):68-74.
  • Pinto A.F., Silva K.R., Guimaraes J.A. (2006) Proteases from Lonomia obliqua venomous secretions: comparison of procoagulant, fibrin(ogen)olytic and amidolytic activities. Toxicon 47(1):113-21.
  • Veiga A.B., Ribeiro J.M., Guimaraes J.A., Francischetti I.M. (2005) A catalog for the transcripts from the venomous structures of the caterpillar Lonomia obliqua: identification of the proteins potentially involved in the coagulation disorder and hemorrhagic syndrome. Gene 355:11-27.
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