Females of this large bodied species can attain snout-vent lengths of over 225 mm, though most adults range from 85 to 150 mm. Adult males are yellowish-brown in color, with the yellow being most pronounced along the sides and the throat. Females and immature males have irregular brown blotches on their dorsal surface. The skin of both sexes is covered by irregularly scattered warts. In sexually active males these warts bear horny spicules. The parotoids are relatively large and often triangular and swollen in appearance. Cranial ridges are well developed. The tympanum is distinct, and the interorbital is concave. The webbing is poorly developed. The nuptial pads in the males are dark on the first 3 fingers (Easteal 1963).
 
Rick Speare has compiled a bibliography on this species up until 1991: Cane toad.
Karyotype: This species has a diploid chromosome (2n) with 5 large pairs and 6 small ones, which makes 22 chromosomes in total (Cole, Lowe, and Wright 1968).

A Spanish-language species account can be found at this website of Instituto Nacional de Biodiversidad (INBio).