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Adenomera hylaedactyla, the Napo tropical bullfrog, is a hyloid frog widely distributed throughout most of the Amazon basin, south to Argentina and Paraguay and occurring on Trinidad Island, Trinidad and Tobago. It is terrestrial, found up to 800 m asl in areas of open vegetation, such as stream and river edges and agricultural clearings. It is generally associated with primary and secondary forest, forest edges and savannah, in Trinidad). De la Riva (1993) indicated that the species has been found in human clearings, roadsides and ditches, and within secondary forest in Bolivia.
Females are slightly larger than males, reaching up to 2.7 cm (1.1 inches). Adults are nocturnal, and breed year round but especially in the rainy season. Females lay a brood of about 15 eggs in foam nests in burrows the males make in the ground; young develop in the nest with nutrition provided from yolk.