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Asterophrys turpicola is a large microhylid frog with adults reaching 65 mm. This frog has a broad head, as wide as the body. It has a large mouth and gape. Distinctive fleshy spines protrude from the eyelids. There are also a few spines on the lower jaw. A crest runs from the eyelid above the tympanum and down to the shoulder, on each side. There are warts on the limbs and sides of its body. Fingers and toes have expanded discs. The color is drab with brown and black shades (Zweifel 2003).