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This large frog is found over a relatively broad, but disjunctive, range of North Africa as well as sub-Saharan Africa. The sexually dimorphic anuran prefers savanna habitat, but is also found in grasslands and certain forests. Eggs are laid in slow moving heavily vegetated streams. As an important predator of mosquitos, Hoplobatrachus occipitalis may play a significant role in preventing spread of certain diseases such as malaria.