Sachatamia albomaculata adult males range from 20.5 to 29 mm in size, while the females reach 22 to 32 mm (Savage 2002). Ground coloration is bluish green, with many light yellow to silver spots on low bumps on the dorsal surfaces (Savage 2002). There is a white stripe on the upper lip and along the margins of the lower limbs. (Savage 2002). The sides of the neck are spotted, while the underside of the limbs is whitish (Savage 2002). Ventrally, these frogs are translucent, and their digestive system is visible (Guyer and Donnelly 2005). A white parietal peritoneal sheath is present, but it does not extend very far posteriorly (Savage 2002). The pericardium is covered by a guanine sheath (Guyer and Donnelly 2005). The bones are green, and are visible when viewed from the dorsal side (Guyer and Donnelly 2005).

The head is as wide as it is long, and rounded when viewed dorsally (Savage 2002). The snout is rounded in profile (Savage 2002). Eyes are large, with gray-gold irises and black reticula, and the pupils are horizontal (Savage 2002). The dorsal skin is granular, with widely scattered bumps (Savage 2002). There is a fleshy fold on the forearm, along the posterior lower edge (Savage 2002). Finger and toe disks are present and truncate (Savage 2002). The outer fingers are webbed, and the toes are moderately webbed (Savage 2002). Males have white nuptial pads on the thumbs (Savage 2002).

 
Their appearance mostly resembles Fleishmann's Glassfrog and the Powdered Glassfrog. Fleishmann's Glassfrog is lighter in color than the Yellow-flecked Glassfrog and has white bones, while the Powdered Glassfrog has larger spots (Guyer and Donnelly, 2005).

The karyotype is 2N=20 (Duellman 1967).

A Spanish-language species account can be found at the website of Instituto Nacional de Biodiversidad (INBio).