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Leptodactylus rhodonotus, the Peru White-lipped Frog, is a large and robust leptodactylid frog, of the Leptodactylus pentadactylus group (Frost 2015). It inhabits primary east Andean montane and lowland rainforests in the upper Amazonian basin of Bolivia and Peru at altitudes between about 300 m (1000 ft; Rio Espiritu Santo collecting site) and 2050 m asl (6700 ft; Parjacti, Bolivia; Reynolds and Foster 1992; Rodríguez and Duellman 1994). This fairly restricted distribution may also extend into Colombia and Brazil (Frost 2015). They are found in degraded habitats (Angulo et al. 2004; Köhler 2000).
Adult L. rhodonotus have a smooth-skinned brown dorsum laterally striped with darker brown, belly a creamy grey-color, and red-brown, darkly reticulated iris. Their legs are cream-colored with bars and have scattered tubercules that also extend onto the dorsum, especially at the posterior of the body. They do not have webbing on their feet. Males (up to almost 8 cm, 3.1 in, snout vent length) are smaller than females (up to 9 cm, 3.5 in. svl; Reynolds and Foster 1992; Rodríguez and Duellman 1994).
These frogs are terrestrial and nocturnal, and live in burrows or under logs and call at night, especially during rain. They lay eggs in foam nests under logs or rocks, which they then sit under during the day. In breeding season, males grow black cornified nuptial spines on their thumbs and elongate black spines on their chest. Tadpoles grow to about 6 cm (2.4 in) in length in stagnant puddles, ditches or slow moving water (Rodríguez and Duellman 1994). Their call has been recorded as a single note, repeated regularly in 6-8 pulses at some times, at others in more complex pulse structures (Köhler and Lötters 1999; Köhler 2000).