Brush rabbits are active all year round and are mainly crepuscular. They come out of their brush area after sunset and remain active until very early morning. They may emerge again a few hours later, until late morning. They rarely emerge in the afternoon, most of that time is spent resting. However, on a nice day, brush rabbits may be observed basking in the sun.
Brush rabbits are wary and secretive animals. They use runways, tunnels, and burrows--although not as extensively as other members of their genus. When pursued, brush rabbits climb trees and scrubs. When brush rabbits are frightened their characteristic response is foot thumping. Thumps may continue for several minutes. Squeals and cries are vocalizations used by brush rabbits in pain or when scared.
To protect themselves from predators, brush rabbits can sit perfectly still for long periods of time. When threatened they run in a zig-zag manner at about 20 to 25 miles an hour.
Although a gregarious species while foraging, brush rabbits are mostly solitary. Brush rabbits inhabit individual home ranges, with male home ranges on average larger than female home ranges (Chapman 1974, Wilson & Ruff 1999, Verts & Carraway 1998).