Zaprionus Coquillett, 1902 is a subgenus of the drosophilid genus Zaprionus Coquillett, 1902, characterized by the presence of an even number of longitudinal white stripes on the frons and the mesonotum. It contains 50 Afrotropical species. Recently, two of its species became invasive, namely Zaprionus indianus Gupta, 1972 and Zaprionus tuberculatus Malloch, 1932, with cosmopolitan and subcosmopolitan distributions, respectively. Most of its species breed on ripe fruits but some are flower breeders. Phyogenetic analyses show the genus to be monophyletic, and a new phylogenetic classification has recently been proposed.
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