Aeromonas hydrophila is a ubiquitous aquatic bacterium living in fresh or brackish water worldwide, and found in large numbers especially in warm conditions (25-35oC). This bacterium is hearty and tolerates aerobic and anaerobic environments, a wide temperature range (it can grow at 4oC), chlorination, pollution, and is also resistant to most common antibiotics.
Aeromonas hydrophila are straight rods with rounded ends usually from 0.3 to 1 micrometer in width, and 1 to 3 micrometers in length and motile via polar flagella. While part of the normal bacterial flora in aquatic ecosystems, this bacterium is opportunistically pathenogenic in aquatic animals, flaring into disease especially when the animals are stressed, disturbed or unhealthy. Aeromonas hydrophila is the most common cause of redleg, a disease contracted by amphibians which causes lesions on their back legs and internal, sometimes fatal hemorrhaging. Fish infected with Aeromonas hydrophila, develop ulcers, tail and fin rot, and other symptoms and can die quickly after contracting symptoms.
While not as pathogenetic in humans as it is in fish and amphibians, (it was not associated with human disease until 1968) when ingested in large quantities from contaminated water or foods (seafood, meats, some vegetables) it may cause gastroenteritis, especially in young children and people who have compromised immune systems. There is some disagreement about what the role of A. hydrophila is in causing gastroenteritis, however. Large outbreaks of Aeromonas-caused gastric illness have never been reported and the frequency of Aeromonas-related disease in the United States is unclear. Aeromonas hydrophila can also enter the body when open skin lacerations are exposed to sources of the bacteria, in these case infection can cause skin inflammation, septicemia (dangerous systemic infection), and rarely it has caused necrotizing fasciitis (flesh-eating disease). An unusual 2012 case of necrotizing fasciitis in a healthy 24-year old brought public attention to A. hydrophila (Lynch 2012).
Aeromonas hydrophila was one of the first species described from genus Aeromonas; isolated from humans and animals in the 1950s. Interest in the genus has jumped hugely in the last 20 years, and since 1980 20 new Aeromonas names were given standing in the literature (LPSN bacterio.net). At least 13 “genospecies” are recognized; it is difficult to distinguish species beyond their species complexes. Not all of these are associated with disease, far less is known about most other species of Aeromonas. The full genome of A. hydrophila was sequenced in 2006.
(CDC 1990; US EPA 2012; Janda and Abbott 2010; LPSN bacterionet, web; Lynch 2012; US FDA 2013; WHO 2002, 2006)
- CDC May 25, 1990. Aeromonas wound infections associated with outdoor activities -- California. MMWR weekly 39(20);334-335,341. Retrieved November 21 2013 from http://www.cdc.gov/mmwr/preview/mmwrhtml/00001628.htm.
- Janda, J.M. and S.L. Abbott, 2010. The Genus Aeromonas: Taxonomy, Pathogenicity, and Infection Clin. Microbiol. Rev. 23:35-73. Available online at http://cmr.asm.org/content/23/1/35.full.pdf+html.
- LPSN bacterio.net. List of Prokaryotic names with standing in nomenclature. Retrieved November 21 2013 from http://www.bacterio.net/a/aeromonas.html.
- Lynch, R. May 15 2012. Flesh-eating bacteria case: could a simple drug have cured it? Los Angeles Times. Retrieved November 21 2013 from http://articles.latimes.com/2012/may/15/nation/la-na-nn-flesh-eating-bacteria-20120515.
- U.S. Environmental Protection Agency (EPA), 2012. Aeromonas detection: what does it mean? Retrieved November 21, 2013 from http://water.epa.gov/lawsregs/rulesregs/sdwa/ucmr/data_aeromonas.cfm.
- US Food and Drug Administration (FDA), Department of Health and Human Services, 22 March 2013. Aeromonas hydrophila. Bad Bug Book: Foodborne Pathogenic Microorganisms and Natural Toxins Handbook. Retrieved November 21 2013 from http://www.fda.gov/food/foodborneillnesscontaminants/causesofillnessbadbugbook/ucm070523.htm
- World Health Organization 2002. Guidelines for drinking water quality, Addendum: Microbiological agents in drinking water, 2nd Edition, Aeromonas. Retrieved November 21 2013 from http://www.who.int/water_sanitation_health/dwq/en/admicrob2.pdf.
- World Health Organization 2006. Guidelines for drinking water quality. Second edition, Volume 2. Health Criteria and other supporting information. ISBN 92 4 154480 5. PDF retrieved November 21 2013 from http://www.who.int/water_sanitation_health/dwq/2edvol2p1.pdf.