The flowers are cross-pollinated by long-tongued bees, bee flies, Halictid bees, butterflies, and skippers. Among long-tongued bees, are such visitors as honeybees, bumblebees, digger bees (Melissodes
spp.), and leaf-cutting bees (Megachile
spp.). Butterfly visitors include Monarchs, Fritillaries, Painted Ladies, Swallowtails, Sulfurs, and Whites. The caterpillars of the butterfly Chlosyne nycteis
(Silvery Checkerspot) feed on the foliage, while the caterpillars of several moths feed on the flowerheads. These latter species include Chlorochlamys chloroleucaria
(Blackberry Looper), Eupithecia miserulata
), Synchlora aerata
(Wavy-Lined Emerald), and Homoeosoma electella
(Sunflower Moth). A small songbird, the Eastern Goldfinch, occasionally eats the seeds during the summer and early fall.