Turbina corymbosa, syn. Rivea corymbosa, the Christmas vine, is a species of morning glory, native throughout Latin America from Mexico in the North to Peru in the South and widely naturalised elsewhere.
Containing an akaloid similar in action to LSD, its seeds and the drug they contain are known as ololiuhqui or ololiuqui.
Known to natives of north and central Mexico by its Nahuatl name Ololiúqui (also spelled ololiuhqui or ololiuqui) and by the south eastern natives as xtabentún (in Mayan), it is a perennial climbing vine with white flowers, often planted as an ornamental plant. This plant also occurs in Cuba, where it usually blooms from early December to February. Its flowers secrete copious amount of nectar, and the honey the bees make from it is very clear and aromatic. It is considered one of the main honey plants from the island.
The Nahuatl word ololiuhqui means "round thing", and refers to the small, brown, oval seeds of the morning glory, not the plant itself, which is called coaxihuitl, "snake-plant", in Nahuatl, and hiedra or bejuco in the Spanish language. The seeds, in Spanish, are sometimes called semilla de la Virgen (seeds of the Virgin Mary). While little of it is known outside of Mexico, its seeds were perhaps the most common psychedelic drug used by the natives.
In 1941, Richard Evans Schultes first identified ololiuhqui as Turbina corymbosa and the chemical composition was first described on August 18, 1960, in a paper by Dr. Albert Hofmann. The seeds contain ergine (LSA), an ergoline alkaloid similar in structure to LSD. The psychedelic properties of Turbina corymbosa and comparison of the potency of different varieties were studied in the Central Intelligence Agency's MKULTRA Subproject 22 in 1956.
The seeds are also used by Native shamans in order to gain knowledge in curing practices and ritual, as well as the causes for the illness.