Like other free-living amoebae, such as Acanthamoeba, Naegleria, and Hartmannella, B. mandrillaris can act as a host for intracellular survival of bacteria, including the causative agent of Legionnaires’ disease, Legionella pneumophila. The ability of amoebae to host bacteria enhances bacterial infectivity for mammalian cells, increases their transmission to susceptible hosts, and may enhance the pathogenicity of the host amoeba.
(Matin et al. 2008)
- Matin, A., R. Siddiqui., S. Jayasekera, and N.A. Khan. 2008. Increasing Importance of Balamuthia mandrillaris. Clinical Microbiology Reviews. 21(3): 435-448.
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