Oncifelis geoffroyi is the least protected of all the small cats, having the lowest AZA conservation rank. They are the most common wild cat in South America. However, they are also the most commonly hunted, and population trends are that they are decreasing. IUCN lists the species as Near Threatened, and change the status to Vulnerable if the downward population trend continues. CITES lists the species as Appendix I.

In the seventies and eighties, Oncifelis geoffroyi was heavily hunted for fur coats, which was legal at the time. It takes approximately 25 cat skins to make one fur coat. 350,000 skins were exported between 1976 and 1979 in Argentina alone, and over 500,000 total from South America in the early eighties. The fur trade has since declined, but about 55,000 pelts are still traded yearly. However, it is believed that most of these pelts are from cats killed that were pests or threats to livestock populations. Commercial hunting has essentially ceased, but these cats are still considered endangered. Habitat destruction also affects these cats. Not enough time has passed since the hunting has been stopped to determine their status, but they are now fully protected (IUCN,1996; Garman,1997).