The giant otter is listed in Appendix I of the Convention on International Trade in Endangered Species (CITES), as Endangered under the United States Endangered Species Act and as Endangered under the IUCN Red List.

1) to continue assessment of predator-prey relationships, including conflicts with subsistence and commercial fishermen
2) to evaluate the positive and negative impacts of tourism in different habitats and implement management guidelines in order to maximize the benefits.
3) To encourage the development of a long-term research and conservation project in the Llanos of Venezuela of Colombia
4) To undertake collaborations between field scientists, zoos and genetic laboratories to evaluate the potential use of genetic analysis tools in giant otter research