Cotton mouse behavior is influenced by the many predators in its environment. Peromyscus gossypinus is active primarily at night. With darkness protecting it from predators, it is able to move about more freely. This behavior has led to well developed senses of sight, smell, and hearing. This species is also cryptically colored and secretive.
- snakes (Serpentes)
- owls (Strigiformes)
- weasels (Mustela)
- foxes (Canidae)
- striped skunks (Mephitis mephitis)
- bobcats (Lynx rufus)
Anti-predator Adaptations: cryptic