Economic Importance for Humans: Negative
Metasepia pfefferi is one of only three known venomous species of cephalopods. The venom that M. pfefferi contains is shown to have similar lethal effects as that of the blue-ringed octopus, Hapolochlaena maculosa. The venom is very toxic and it may possibly be able to quickly kill an adult human.
Negative Impacts: injures humans (bites or stings, venomous )
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