Ocellated turkey adults and young are preyed on by gray foxes, margay cats, ocelots, raccoons, coatis, cougars, jaguarundi, jaguars, snakes, and birds of prey. Humans also hunt adult turkeys for food.
Ocellated turkeys run fast and fly well, which help them to escape predators. Both male and female adults make a loud cluck-putt alarm call, which warns others in the flock. Birds roost in trees where they are safe from ground predators.
- gray foxes (Urocyon cinereoargenteus)
- ocelots (Leopardus pardalis)
- jaguarundis (Puma yagouaroundi)
- margay cats (Leopardus wiedii)
- northern raccoons (Procyon lotor)
- white-nosed coatis (Nasua narica)
- cougars (Puma concolor)
- jaguars (Panthera onca)
- snakes (Serpentes)
- birds of prey (Falconiformes)
- humans (Homo sapiens)