Holothurians in general are most vulnerable in their larval stage. Some holothurians discharge sticky tubules, known as   Cuvierian tubules, at a potential predator. The tubules are sticky clusters found at the base of the respiratory tree. Predators include sea stars, fish, gastropods, and crustaceans as well as humans. Holothurians also expell their organs, which are later regenerated. This is a seasonal event, but is also thought to be an anti-predator defense.

Known Predators:

• sea stars, Asteroidea 
• gastropods, Gastropoda 
• crustaceans, Crustacea 
• fish
• humans, Homo sapiens 

Anti-predator Adaptations: cryptic