Dermatobia hominis reach sexual maturity soon after emergence from the puparium, and viable eggs may be laid as of the second day of adulthood. An egg, after being glued onto a paratenic host for transport to the vertebrate host requires 5-9 days to develop, after which it requires an additional 27-128 days to pass through the three larval stages inside the definitive host. Normally, about 12, 18, and 12 days are required for a larva to pass through the first, second, and third instars respectively. At the end of the larval period, the third larval instar exits the definitive host's body and drops onto the soil, after which it burrows deeply into the soil or other available debris and pupates within a period of 2-3 days. At the end of the pupation period, which takes somewhere between 27-78 days depending on seasonal variation in soil temperature, the adult emerges and becomes sexually active within two hours.
Development - Life Cycle: metamorphosis