Mexican red-knee spiders are considered "near threatened" by the IUCN and are on Apendex II of CITES, which limits trade of individuals between countries. It is illegal to catch and sell wild individuals. Mexican red-knee spiders are at risk because of the pet trade and habitat destruction.
US Federal List: no special status
CITES: appendix ii
IUCN Red List of Threatened Species: lower risk - near threatened